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VPS11 antibody (Center)

VPS11 Reactivity: Human WB, IF, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856524
  • Target See all VPS11 Antibodies
    VPS11 (Vacuolar Protein Sorting 11 Homolog (VPS11))
    Binding Specificity
    • 8
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 31
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 27
    • 3
    • 1
    Rabbit
    Clonality
    • 28
    • 3
    Polyclonal
    Conjugate
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    This VPS11 antibody is un-conjugated
    Application
    • 29
    • 19
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio), Medaka, Xenopus tropicalis, Cow (Bovine)
    Cross-Reactivity (Details)
    Mouse (100 %), Rat (100 %), Zebrafish (85 %), Japanese Medaka (100 %), Xenopus Tropicalis (92 %), Bovine (100 %)
    Characteristics
    Rabbit Polyclonal antibody to VPS11 (vacuolar protein sorting 11 homolog (S. cerevisiae))
    VPS11 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human VPS11. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product VPS11 Primary Antibody
  • Application Notes
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Comment

    Positive Control: 293T , HepG2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    VPS11 (Vacuolar Protein Sorting 11 Homolog (VPS11))
    Alternative Name
    VPS11 (VPS11 Products)
    Synonyms
    zgc:112329 antibody, ATVPS11 antibody, F5G3.7 antibody, F5G3_7 antibody, vacuolar protein sorting 11 antibody, DDBDRAFT_0204454 antibody, DDBDRAFT_0234135 antibody, DDB_0204454 antibody, DDB_0234135 antibody, end1 antibody, pep5 antibody, hvps11 antibody, rnf108 antibody, 1200011A11Rik antibody, END1 antibody, PEP5 antibody, RNF108 antibody, hVPS11 antibody, VPS11, CORVET/HOPS core subunit antibody, vacuolar protein sorting 11 antibody, vacuolar protein sorting protein 11 antibody, VPS11, CORVET/HOPS core subunit S homeolog antibody, Vacuolar peripheral membrane protein similar to S. cerevisiae PEP5 (YMR231W); C terminus is almost identical to nonallelic CaP19.1278 antibody, 7-fold repeat in clathrin and VPS proteins repeat-containing protein antibody, vacuolar protein sorting-associated protein 11 homolog antibody, VPS11 CORVET/HOPS core subunit antibody, VPS11 antibody, vps11 antibody, MCYG_02909 antibody, vps11.S antibody, LOC100632536 antibody, Vps11 antibody
    Background
    Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.

    Cellular Localization: Late endosome membrane, Peripheral membrane protein, Cytoplasmic side , Lysosome membrane, Peripheral membrane protein, Cytoplasmic side
    Molecular Weight
    108 kDa
    Gene ID
    55823
    Pathways
    SARS-CoV-2 Protein Interactome
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