ITPA antibody

Catalog No. ABIN2856410

Product Details anti-ITPA Antibody

Target: ITPA (Inosine Triphosphatase (ITPA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITPA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to ITPase (inosine triphosphatase (nucleoside triphosphate pyrophosphatase))
ITPase antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ITPase. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ITPA

Target: ITPA (Inosine Triphosphatase (ITPA))

Alternative Name: inosine triphosphatase (ITPA Products)

Synonyms: DDBDRAFT_0215619 antibody, DDBDRAFT_0238062 antibody, DDB_0215619 antibody, DDB_0238062 antibody, 2010016I08Rik antibody, AU020102 antibody, Itp antibody, C20orf37 antibody, HLC14-06-P antibody, dJ794I6.3 antibody, ITPase antibody, NTPase antibody, si:ch73-18j6.1 antibody, si:dkey-19f21.1 antibody, inosine triphosphatase antibody, inosine triphosphatase (nucleoside triphosphate pyrophosphatase) antibody, Inosine triphosphate pyrophosphatase antibody, inosine triphosphatase S homeolog antibody, itpa antibody, ITPA antibody, LOC733043 antibody, Itpa antibody, pco148511 antibody, itpa.S antibody

Background: The protein encoded by this gene hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. The encoded protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency. Two transcript variants encoding two different isoforms have been found for this gene. Also, at least two other transcript variants have been identified which are probably regulatory rather than protein-coding.

Cellular Localization: Cytoplasm

Molecular Weight: 21 kDa

Gene ID: 3704

UniProt: Q9BY32