HNRNPR antibody (N-Term)

Catalog No. ABIN2856397

Product Details anti-HNRNPR Antibody

Target: HNRNPR (Heterogeneous Nuclear Ribonucleoprotein R (HNRNPR))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPR antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to hnRNP R (heterogeneous nuclear ribonucleoprotein R)
hnRNP R antibody [N1N2], N-term

Purification: Purified by antigen-affinity chromatography.

Grade: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human hnRNP R. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for HNRNPR

Target: HNRNPR (Heterogeneous Nuclear Ribonucleoprotein R (HNRNPR))

Alternative Name: heterogeneous nuclear ribonucleoprotein R (HNRNPR Products)

Synonyms: hnrpr antibody, wu:fb97a09 antibody, wu:fe01h03 antibody, zgc:56523 antibody, HNRPR antibody, hnRNP R antibody, hnRNP-R antibody, 2610003J05Rik antibody, 2610528B01Rik antibody, Hnrpr antibody, heterogeneous nuclear ribonucleoprotein R antibody, hnrnpr antibody, HNRNPR antibody, Hnrnpr antibody

Background: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif. Multiple alternatively spliced transcript variants have been found for this gene.

Cellular Localization: Nucleus , nucleoplasm

Molecular Weight: 71 kDa

Gene ID: 10236

UniProt: O43390