NCBP1 antibody (N-Term)

Catalog No. ABIN2856327

Product Details anti-NCBP1 Antibody

Target: NCBP1 (Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to NCBP1 (nuclear cap binding protein subunit 1, 80 kDa)
NCBP1 antibody [N2], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CBP80. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for NCBP1

Target: NCBP1 (Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1))

Alternative Name: nuclear cap binding protein subunit 1 (NCBP1 Products)

Synonyms: CBP80 antibody, CG7035 antibody, Dmel\\CG7035 antibody, EG:84H4.3 antibody, ncbp antibody, sto1 antibody, cbp80 antibody, AU014645 antibody, AW538051 antibody, NCBP antibody, Sto1 antibody, ncbp1 antibody, ABA HYPERSENSITIVE 1 antibody, ATCBP80 antibody, CAP-BINDING PROTEIN 80 antibody, ENS antibody, ENSALADA antibody, NUCLEAR CAP-BINDING PROTEIN CBP80 antibody, T10F5.8 antibody, T10F5_8 antibody, cap binding protein 80 antibody, nuclear cap binding protein subunit 1 antibody, nuclear cap binding protein subunit 1 S homeolog antibody, nuclear cap binding protein subunit 1, 80kDa antibody, nuclear cap binding protein subunit 1 L homeolog antibody, ARM repeat superfamily protein antibody, Nuclear cap-binding protein subunit 1-A antibody, Nuclear cap-binding protein subunit 1 antibody, Cbp80 antibody, ncbp1 antibody, ncbp1.S antibody, NCBP1 antibody, Ncbp1 antibody, ncbp1.L antibody, ABH1 antibody, nbp1a antibody, ncbp-1 antibody

Background: The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.

Cellular Localization: Nucleus

Molecular Weight: 92 kDa

Gene ID: 4686

UniProt: Q09161

Pathways: Ribonucleoprotein Complex Subunit Organization, Photoperiodism, Methionine Biosynthetic Process