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KPNA4 antibody (C-Term)

KPNA4 Reactivity: Human ICC, IF, IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856326
  • Target See all KPNA4 products
    KPNA4 (Importin Subunit alpha-3 (KPNA4))
    Binding Specificity
    C-Term
    Reactivity
    Human
    Host
    Rabbit
    Clonality
    Polyclonal
    Application
    Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Rabbit Polyclonal antibody to KPNA4 (karyopherin alpha 4 (importin alpha 3))
    KPNA4 antibody [C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human KPNA4. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: 293T , HepG2 , Molt-4 , Rat2 , Neuro2A , GL261 , C8D30 , NIH-3T3 , BCL-1 , HeLa

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.04 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Yang, Chiang, Chen, Lee, Wu, Tsou, Yang, Chang, Lin: "Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58)." in: Journal of biomedical science, Vol. 22, pp. 33, (2016) (PubMed).

  • Target
    KPNA4 (Importin Subunit alpha-3 (KPNA4))
    Alternative Name
    karyopherin subunit alpha 4 (KPNA4 Products)
    Synonyms
    IPOA3 antibody, QIP1 antibody, SRP3 antibody, karyopherin subunit alpha 4 antibody, KPNA4 antibody
    Background
    The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.

    Molecular Weight
    58 kDa
    Gene ID
    3840
    UniProt
    O00629
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