KPNA4 antibody (C-Term)
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- Target See all KPNA4 products
- KPNA4 (Importin Subunit alpha-3 (KPNA4))
- Binding Specificity
- C-Term
- Reactivity
- Human
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
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Rabbit Polyclonal antibody to KPNA4 (karyopherin alpha 4 (importin alpha 3))
KPNA4 antibody [C3], C-term - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human KPNA4. The exact sequence is proprietary.
- Isotype
- IgG
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: 293T , HepG2 , Molt-4 , Rat2 , Neuro2A , GL261 , C8D30 , NIH-3T3 , BCL-1 , HeLa
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.04 mg/mL
- Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58)." in: Journal of biomedical science, Vol. 22, pp. 33, (2016) (PubMed).
: "
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Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58)." in: Journal of biomedical science, Vol. 22, pp. 33, (2016) (PubMed).
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- Target
- KPNA4 (Importin Subunit alpha-3 (KPNA4))
- Alternative Name
- karyopherin subunit alpha 4 (KPNA4 Products)
- Synonyms
- IPOA3 antibody, QIP1 antibody, SRP3 antibody, karyopherin subunit alpha 4 antibody, KPNA4 antibody
- Background
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The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
- Molecular Weight
- 58 kDa
- Gene ID
- 3840
- UniProt
- O00629
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