WHSC1 antibody (N-Term)

Catalog No. ABIN2856315

Product Details anti-WHSC1 Antibody

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WHSC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): Mouse (83 %)

Characteristics: Rabbit Polyclonal antibody to NSD2 (Wolf-Hirschhorn syndrome candidate 1)
NSD2 antibody [N1], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human NSD2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: Molt-4 , Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for WHSC1

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Alternative Name: NSD2 (WHSC1 Products)

Synonyms: WHSC1 antibody, fc12c04 antibody, wu:fc12c04 antibody, wu:fi20c01 antibody, si:rp71-77d7.2 antibody, whs antibody, nsd2 antibody, trx5 antibody, mmset antibody, reiibp antibody, MMSET antibody, NSD2 antibody, REIIBP antibody, TRX5 antibody, WHS antibody, RGD1565590 antibody, 5830445G22Rik antibody, 9430010A17Rik antibody, AW555663 antibody, C130020C13Rik antibody, D030027O06Rik antibody, D930023B08Rik antibody, Whsc1l antibody, mKIAA1090 antibody, nuclear receptor binding SET domain protein 2 antibody, Wolf-Hirschhorn syndrome candidate 1 antibody, NSD2 antibody, nsd2 antibody, WHSC1 antibody, Nsd2 antibody

Background: This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4,14)(p16.3,q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

Molecular Weight: 152 kDa

Gene ID: 7468

Pathways: SARS-CoV-2 Protein Interactome