DYX1C1 antibody (C-Term)

Catalog No. ABIN2856307

Product Details anti-DYX1C1 Antibody

Target: DYX1C1 (Dyslexia Susceptibility 1 Candidate 1 (DYX1C1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYX1C1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Chimpanzee

Cross-Reactivity (Details): Chimpanzee (100 %)

Characteristics: Rabbit polyclonal antibody to Dyslexia susceptibility 1 candidate 1 (dyslexia susceptibility 1 candidate 1)
DYX1C1 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human DYX1C1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.92 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for DYX1C1

Target: DYX1C1 (Dyslexia Susceptibility 1 Candidate 1 (DYX1C1))

Alternative Name: Dyslexia Susceptibility 1 Candidate 1 (DYX1C1 Products)

Synonyms: DYX1 antibody, DYXC1 antibody, EKN1 antibody, RD antibody, 1700010I24Rik antibody, Edem2 antibody, Ekn1 antibody, zgc:77853 antibody, LOC100220614 antibody, dynein axonemal assembly factor 4 antibody, dyslexia susceptibility 1 candidate 1 antibody, dynein axonemal assembly factor 4 L homeolog antibody, DNAAF4 antibody, Dyx1c1 antibody, Dnaaf4 antibody, dnaaf4 antibody, DYX1C1 antibody, dnaaf4.L antibody

Background: This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternate splicing results in multiple transcript variants.

Cellular Localization: Nucleus

Molecular Weight: 49 kDa

Gene ID: 161582

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling