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Adenylate Kinase 1 antibody

KO Validated AK1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856252
  • Target See all Adenylate Kinase 1 (AK1) Antibodies
    Adenylate Kinase 1 (AK1)
    Reactivity
    • 85
    • 25
    • 19
    • 10
    • 9
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Host
    • 82
    • 10
    • 8
    Rabbit
    Clonality
    • 91
    • 9
    Polyclonal
    Conjugate
    • 48
    • 12
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Adenylate Kinase 1 antibody is un-conjugated
    Application
    • 59
    • 37
    • 28
    • 24
    • 13
    • 13
    • 10
    • 9
    • 9
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Rabbit Polyclonal antibody to Adenylate kinase 1 (adenylate kinase 1)
    Adenylate kinase 1 antibody [N1C3]
    Purification
    Purified by antigen-affinity chromatography.
    Grade
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Adenylate kinase 1. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product AK1 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Mouse brown adipose tissue

    Validation: KO/KD

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.4 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Adenylate Kinase 1 (AK1)
    Alternative Name
    adenylate kinase 1 (AK1 Products)
    Synonyms
    ADK-1 antibody, AK1 antibody, CG17146 antibody, DAK1 antibody, Dak1 antibody, Dmel\\CG17146 antibody, adk1 antibody, bs34e10.y1 antibody, ak5 antibody, ADENYLATE KINASE 1 antibody, MLE2.3 antibody, MLE2_3 antibody, adenylate kinase 1 antibody, Ak-1 antibody, B430205N08Rik antibody, Ak 1 antibody, zgc:91930 antibody, Myokinase antibody, Adenylate kinase 1 antibody, adenylate kinase 1 antibody, Adk1 antibody, ak1 antibody, AK1 antibody, ADK1 antibody, Ak1 antibody
    Background
    Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.

    Cellular Localization: Cytoplasm
    Molecular Weight
    22 kDa
    Gene ID
    203
    UniProt
    P00568
    Pathways
    Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
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