WNT11 antibody (Center)
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- Target See all WNT11 Antibodies
- WNT11 (Wingless-Type MMTV Integration Site Family, Member 11 (WNT11))
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Binding Specificity
- Center
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This WNT11 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Cross-Reactivity
- Chicken, Rat (Rattus), Xenopus laevis, Cow (Bovine)
- Cross-Reactivity (Details)
- Chicken (85 %), Rat (96 %), Xenopus laevis (81 %), Bovine (98 %)
- Characteristics
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Rabbit Polyclonal antibody to WNT11 (wingless-type MMTV integration site family, member 11)
WNT11 antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human WNT11. The exact sequence is proprietary.
- Isotype
- IgG
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- Application Notes
- Suggested dilution Reference ICC/IF 1:100-1:1000* Immunohistochemistry Assay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* ImmunohistochemistryAssay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- Comment
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Positive Control: 293T , A431 , HeLa , HepG2 , mouse heart
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS, 20 % Glycerol ( pH 7). 0.025 % ProClin 300 was added as a preservative.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- WNT11 (Wingless-Type MMTV Integration Site Family, Member 11 (WNT11))
- Alternative Name
- WNT11 (WNT11 Products)
- Synonyms
- HWNT11 antibody, Wnt11r antibody, Xwnt11 antibody, Xwnt-11 antibody, wnt11-r antibody, XWnt-11 antibody, wnt11b antibody, wnt11b-2 antibody, Slb/Wnt11 antibody, cb748 antibody, slb antibody, Wnt12 antibody, WNT11 antibody, wnt-11 antibody, xwnt11 antibody, Wnt family member 11 antibody, wingless-type MMTV integration site family member 11 L homeolog antibody, wingless-type MMTV integration site family, member 11B antibody, wingless-type MMTV integration site family, member 11 antibody, protein Wnt-11-like antibody, wingless-type MMTV integration site family, member 10B antibody, wingless-type MMTV integration site family, member 11B L homeolog antibody, WNT11 antibody, Wnt11 antibody, wnt11.L antibody, wnt11b antibody, wnt11 antibody, LOC100229189 antibody, Wnt10b antibody, wnt11b.L antibody
- Background
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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97 % , 85 %, and 63 % amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome.
Cellular Localization: Secreted , extracellular space , extracellular matrix - Molecular Weight
- 39 kDa
- Gene ID
- 7481
- Pathways
- WNT Signaling, Cell-Cell Junction Organization
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