WBSCR22 antibody (Center)

Catalog No. ABIN2856201

Product Details anti-WBSCR22 Antibody

Target: WBSCR22 (Williams Beuren Syndrome Chromosome Region 22 (WBSCR22))

Binding Specificity: Center

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WBSCR22 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Characteristics: Rabbit Polyclonal antibody to WBSCR22 (Williams Beuren syndrome chromosome region 22)
WBSCR22 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human WBSCR22. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:500-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:500-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: HeLa , HCT116 , *A375M ,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.42 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-WBSCR22 antibody (ABIN2856201)

Baxter, Voronkov, Poolman, Galli, Pinali, Goosey, Knight, Krakowiak, Maidstone, Iqbal, Zi, Prehar, Cartwright, Gibbs, Matthews, Adamson, Humphreys, Rebelo-Guiomar, Minczuk, Bechtold, Loudon, Ray: "Cardiac mitochondrial function depends on BUD23 mediated ribosome programming." in: eLife, Vol. 9, (2020) (PubMed).

Target Details for WBSCR22

Target: WBSCR22 (Williams Beuren Syndrome Chromosome Region 22 (WBSCR22))

Alternative Name: WBSCR22 (WBSCR22 Products)

Synonyms: MGC82375 antibody, wbmt antibody, pp3381 antibody, hussy-3 antibody, hasj4442 antibody, zgc:162306 antibody, HASJ4442 antibody, HUSSY-3 antibody, MERM1 antibody, PP3381 antibody, WBMT antibody, 1110003N24Rik antibody, Williams-Beuren syndrome chromosome region 22 antibody, BUD23, rRNA methyltransferase and ribosome maturation factor L homeolog antibody, BUD23, rRNA methyltransferase and ribosome maturation factor antibody, williams Beuren syndrome chromosome region 22 antibody, hypothetical protein antibody, WBSCR22 antibody, bud23.L antibody, bud23 antibody, CpipJ_CPIJ001394 antibody, PAAG_00857 antibody, MCYG_07273 antibody, PGTG_07527 antibody, PGTG_12505 antibody, BUD23 antibody, Bud23 antibody

Background: This gene encodes a protein containing a nuclear localization signal and an S-adenosyl-L-methionine binding motif typical of methyltransferases, suggesting that the encoded protein may act on DNA methylation. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23.

Cellular Localization: Nucleus

Molecular Weight: 32 kDa

Gene ID: 114049