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FOLR2 antibody

FOLR2 Reactivity: Human WB, IHC, IHC (p), IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856196
  • Target See all FOLR2 Antibodies
    FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
    Reactivity
    • 51
    • 19
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 45
    • 9
    • 1
    Rabbit
    Clonality
    • 44
    • 10
    • 1
    Polyclonal
    Conjugate
    • 27
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FOLR2 antibody is un-conjugated
    Application
    • 42
    • 29
    • 15
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Rabbit Polyclonal antibody to Folate receptor beta (folate receptor 2 (fetal))
    Folate receptor beta antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Folate Receptor beta. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product FOLR2 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.2 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Meredith, MacNeil, Trasler, Baltz: "Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size." in: Biology of reproduction, Vol. 94, Issue 6, pp. 125, (2017) (PubMed).

  • Target
    FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
    Alternative Name
    folate receptor beta (FOLR2 Products)
    Synonyms
    FOLR2 antibody, BETA-HFR antibody, FBP antibody, FBP/PL-1 antibody, FR-BETA antibody, FR-P3 antibody, FBP2 antibody, Folbp-2 antibody, Folbp2 antibody, folate receptor 1 antibody, folate receptor beta antibody, folate receptor 2 (fetal) antibody, FOLR1 antibody, FOLR2 antibody, Folr2 antibody
    Background
    The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.

    Cellular Localization: Cell membrane, Lipid-anchor , GPI-anchor , Secreted
    Molecular Weight
    29 kDa
    Gene ID
    2350
    UniProt
    P14207
    Pathways
    Dicarboxylic Acid Transport
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