Selenoprotein P antibody

Catalog No. ABIN2856147

Product Details anti-Selenoprotein P Antibody

Target: Selenoprotein P (SEPP1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Selenoprotein P antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to Selenoprotein P (selenoprotein P, plasma, 1)
Selenoprotein P antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Selenoprotein P. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Jurkat , Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Selenoprotein P

Target: Selenoprotein P (SEPP1)

Alternative Name: selenoprotein P (SEPP1 Products)

Synonyms: SELP antibody, SeP antibody, AU018766 antibody, D15Ucla1 antibody, Se-P antibody, selp antibody, sepp1 antibody, MGC88974 antibody, SEPP1 antibody, SEP antibody, DKFZp459B039 antibody, SePPb antibody, SelPb antibody, cb689 antibody, fb59b06 antibody, id:ibd5022 antibody, sePb antibody, wu:fb59b06 antibody, SePPa antibody, SelPa antibody, cb688 antibody, wu:fa55a04 antibody, wu:fb38a09 antibody, wu:fj79f04 antibody, selenoprotein P antibody, selenoprotein P1 antibody, selenoprotein P2-like antibody, selenoprotein P2 antibody, SELENOP antibody, Selenop antibody, SELENOP1 antibody, selenop2l antibody, SeP antibody, selenop2 antibody, selenop antibody

Background: This gene encodes a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is an extracellular glycoprotein, and is unusual in that it contains 10 Sec residues per polypeptide. It is a heparin-binding protein that appears to be associated with endothelial cells, and has been implicated to function as an antioxidant in the extracellular space. Several transcript variants, encoding either the same or different isoform, have been found for this gene.

Cellular Localization: Secreted

Molecular Weight: 41 kDa

Gene ID: 6414

UniProt: P49908