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Complement C2 antibody

Reactivity: Human WB, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856098
  • Target See all Complement C2 Antibodies
    Complement C2
    Reactivity
    • 59
    • 10
    • 10
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 54
    • 7
    • 1
    Rabbit
    Clonality
    • 57
    • 5
    Polyclonal
    Conjugate
    • 33
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Complement C2 antibody is un-conjugated
    Application
    • 36
    • 22
    • 13
    • 13
    • 9
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit Polyclonal antibody to Complement C2 (complement component 2)
    Complement C2 antibody [N3C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Complement C2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product Complement C2 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Complement C2
    Abstract
    Complement C2 Products
    Synonyms
    CO2 antibody, complement C2 antibody, complement component 2 (within H-2S) antibody, C2 antibody
    Background
    Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.

    Cellular Localization: Secreted
    Molecular Weight
    83 kDa
    Gene ID
    717
    UniProt
    P06681
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