PPP1CB antibody (Center)

Catalog No. ABIN2856078

Product Details anti-PPP1CB Antibody

Target: PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))

Binding Specificity: Center

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1CB antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Rat (Rattus), Xenopus laevis, Xenopus tropicalis, Pig (Porcine), Chicken, Rhesus Monkey, Cow (Bovine)

Cross-Reactivity (Details): Rat (100 %), Xenopus laevis (100 %), Xenopus Tropicalis (100 %), Pig (100 %), Chicken (100 %), Rhesus Monkey (100 %), Bovine (100 %)

Characteristics: Rabbit Polyclonal antibody to PPP1CB (protein phosphatase 1, catalytic subunit, beta isozyme)
PPP1CB antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PPP1CB. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , mouse brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PPP1CB

Target: PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))

Alternative Name: PPP1CB (PPP1CB Products)

Synonyms: PP-1B antibody, PP1B antibody, PP1beta antibody, PPP1CD antibody, 1200010B19 antibody, ik:tdsubc_2f2 antibody, si:zc214p16.4 antibody, wu:fa09h01 antibody, wu:fa11e06 antibody, xx:tdsubc_2f2 antibody, PP2CB antibody, Ppp1cb antibody, protein phosphatase 1 catalytic subunit beta antibody, protein phosphatase 1, catalytic subunit, beta isoform antibody, protein phosphatase 1, catalytic subunit, beta isozyme L homeolog antibody, protein phosphatase 1, catalytic subunit, beta isozyme antibody, serine/threonine-protein phosphatase PP1-beta catalytic subunit antibody, protein phosphatase 1B, magnesium dependent, beta isoform antibody, PPP1CB antibody, Ppp1cb antibody, ppp1cb.L antibody, ppp1cb antibody, LOC100224238 antibody, Ppm1b antibody

Background: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.

Cellular Localization: Cytoplasm

Molecular Weight: 37 kDa

Gene ID: 5500

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism