GABRA2 antibody (Center)

Catalog No. ABIN2856076

Product Details anti-GABRA2 Antibody

Target: GABRA2 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2))

Binding Specificity: Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRA2 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Rhesus Monkey, Cow (Bovine)

Cross-Reactivity (Details): Mouse (100 %), Rat (100 %), Rhesus Monkey (100 %), Bovine (100 %)

Characteristics: Rabbit polyclonal antibody to GABA A Receptor alpha 2 (gamma-aminobutyric acid (GABA) A receptor, alpha 2)
GABA A Receptor alpha 2 antibody [N1C2]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human GABA A Receptor alpha 2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: NT2D1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GABRA2

Target: GABRA2 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2))

Alternative Name: GABA A Receptor alpha 2 (GABRA2 Products)

Synonyms: C630048P16Rik antibody, Gabra-2 antibody, gamma-aminobutyric acid type A receptor alpha2 subunit antibody, gamma-aminobutyric acid type A receptor alpha1 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, alpha 2 antibody, gamma-aminobutyric acid (GABA) A receptor, alpha 2 S homeolog antibody, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 antibody, GABRA2 antibody, GABRA1 antibody, gabra2 antibody, Gabra2 antibody, gabra2.S antibody

Background: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Cellular Localization: Cell junction , synapse , postsynaptic cell membrane, Multi-pass membrane protein , Cell membrane, Multi-pass membrane protein

Molecular Weight: 51 kDa

Gene ID: 2555