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MMP17 antibody

MMP17 Reactivity: Human WB, IHC (p), ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856073
  • Target See all MMP17 Antibodies
    MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))
    Reactivity
    • 48
    • 33
    • 10
    • 1
    • 1
    Human
    Host
    • 61
    • 3
    Rabbit
    Clonality
    • 53
    • 11
    Polyclonal
    Conjugate
    • 21
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MMP17 antibody is un-conjugated
    Application
    • 47
    • 28
    • 19
    • 14
    • 14
    • 8
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit Polyclonal antibody to MMP17 (matrix metallopeptidase 17 (membrane-inserted))
    MMP17 antibody [N2C2], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human MMP17. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: HeLa

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.74 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))
    Alternative Name
    matrix metallopeptidase 17 (MMP17 Products)
    Synonyms
    MT4-MMP antibody, CBTF antibody, DRBF antibody, DRBP76 antibody, MMP4 antibody, MPHOSPH4 antibody, MPP4 antibody, NF-AT-90 antibody, NF110 antibody, NF110b antibody, NF90 antibody, NF90a antibody, NF90b antibody, NFAR antibody, NFAR-1 antibody, NFAR2 antibody, TCP110 antibody, TCP80 antibody, MT4MMP antibody, MTMMP4 antibody, mmp17 antibody, matrix metallopeptidase 17 antibody, interleukin enhancer binding factor 3 antibody, matrix metallopeptidase 17a antibody, MMP17 antibody, ILF3 antibody, Mmp17 antibody, mmp17a antibody
    Background
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.

    Cellular Localization: Isoform Long: Cell membrane, Lipid-anchor , GPI-anchor, Extracellular side , Secreted , extracellular space , extracellular matrix
    Molecular Weight
    67 kDa
    Gene ID
    4326
    UniProt
    Q9ULZ9
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