MTMR14 antibody

Catalog No. ABIN2856063

Product Details anti-MTMR14 Antibody

Target: MTMR14 (Myotubularin Related Protein 14 (MTMR14))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTMR14 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to MTMR14 (myotubularin related protein 14)
MTMR14 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MTMR14. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Molt-4

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MTMR14

Target: MTMR14 (Myotubularin Related Protein 14 (MTMR14))

Alternative Name: myotubularin related protein 14 (MTMR14 Products)

Synonyms: fc14d11 antibody, wu:fc14d11 antibody, MGC131146 antibody, C3orf29 antibody, 1110061O04Rik antibody, AW553738 antibody, C76151 antibody, RGD1304842 antibody, jumpy antibody, myotubularin related protein 14 antibody, myotubularin-related protein 14 antibody, myotubularin related protein 14 S homeolog antibody, mtmr14 antibody, LOC703936 antibody, mtmr14.S antibody, MTMR14 antibody, Mtmr14 antibody

Background: This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.

Cellular Localization: Cytoplasm

Molecular Weight: 72 kDa

Gene ID: 64419

UniProt: Q8NCE2

Pathways: Inositol Metabolic Process