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PCCB antibody (Center)

PCCB Reactivity: Human, Mouse WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856061
  • Target See all PCCB Antibodies
    PCCB (Propionyl CoA Carboxylase beta Polypeptide (PCCB))
    Binding Specificity
    • 15
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 37
    • 30
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 51
    • 2
    Rabbit
    Clonality
    • 53
    Polyclonal
    Conjugate
    • 23
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PCCB antibody is un-conjugated
    Application
    • 42
    • 16
    • 13
    • 13
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Cow (Bovine), Pig (Porcine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
    Cross-Reactivity (Details)
    Pig (94 %), Rat (91 %), Xenopus laevis (90 %), Zebrafish (90 %), Bovine (97 %)
    Characteristics
    Rabbit Polyclonal antibody to PCCB (propionyl Coenzyme A carboxylase, beta polypeptide)
    PCCB antibody [N2C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human PCCB. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Comment

    Positive Control: HepG2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.54 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    PCCB (Propionyl CoA Carboxylase beta Polypeptide (PCCB))
    Alternative Name
    PCCB (PCCB Products)
    Synonyms
    1300012P06Rik antibody, AI314687 antibody, R74805 antibody, propionyl-CoA carboxylase beta subunit antibody, propionyl Coenzyme A carboxylase, beta polypeptide antibody, PCCB antibody, Pccb antibody
    Background
    The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2).

    Cellular Localization: Mitochondrion matrix
    Molecular Weight
    58 kDa
    Gene ID
    5096
    Pathways
    Monocarboxylic Acid Catabolic Process
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