ARNTL antibody

Catalog No. ABIN2856024

Product Details anti-ARNTL Antibody

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARNTL antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to MOP3 (aryl hydrocarbon receptor nuclear translocator-like)
MOP3 antibody [N1N3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human BMAL1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse brain , ARNTL transfected 293T cell

Validation: Orthogonal, Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.65 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ARNTL

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Alternative Name: aryl hydrocarbon receptor nuclear translocator like (ARNTL Products)

Synonyms: BMAL1 antibody, BMAL1c antibody, JAP3 antibody, MOP3 antibody, PASD3 antibody, TIC antibody, bHLHe5 antibody, Bmal1 antibody, ARNTL antibody, xBmal1 antibody, arntl antibody, Arnt3 antibody, BMAL1b antibody, bmal1b' antibody, aryl hydrocarbon receptor nuclear translocator like antibody, aryl hydrocarbon receptor nuclear translocator-like antibody, aryl hydrocarbon receptor nuclear translocator like S homeolog antibody, ARNTL antibody, Arntl antibody, arntl.S antibody, arntl antibody

Background: The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.

Cellular Localization: Nucleus

Molecular Weight: 69 kDa

Gene ID: 406

UniProt: O00327

Pathways: Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Warburg Effect