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ADAM10 antibody

ADAM10 Reactivity: Human WB, ICC, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855998
  • Target See all ADAM10 Antibodies
    ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
    Reactivity
    • 66
    • 29
    • 29
    • 1
    • 1
    • 1
    Human
    Host
    • 54
    • 12
    • 2
    • 1
    Rabbit
    Clonality
    • 47
    • 22
    Polyclonal
    Conjugate
    • 30
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADAM10 antibody is un-conjugated
    Application
    • 42
    • 15
    • 14
    • 14
    • 13
    • 13
    • 7
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Drosophila melanogaster, Human, Mouse
    Characteristics
    Rabbit Polyclonal antibody to ADAM10 (disintegrin and metalloproteinase domain-containing protein 10)
    ADAM10 antibody [N2C1], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human ADAM10. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product ADAM10 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: THP-1

    Validation: Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.48 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
    Alternative Name
    ADAM metallopeptidase domain 10 (ADAM10 Products)
    Background
    Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin.

    Cellular Localization: Cell membrane , Endomembrane system
    Molecular Weight
    84 kDa
    Gene ID
    102
    UniProt
    O14672
    Pathways
    Notch Signaling, EGFR Signaling Pathway
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