CREB3L1 antibody (C-Term)

Catalog No. ABIN2855962

Product Details anti-CREB3L1 Antibody

Target: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREB3L1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to CREB3L1 (cAMP responsive element binding protein 3-like 1)
CREB3L1 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CREB3L1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HepG2 , Molt-4 , 293T , A431 , HeLa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for CREB3L1

Target: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Alternative Name: cAMP responsive element binding protein 3 like 1 (CREB3L1 Products)

Synonyms: CREB3L1 antibody, OASIS antibody, Oasis antibody, diacylglycerol kinase-like antibody, cAMP responsive element binding protein 3 like 1 antibody, cAMP responsive element binding protein 3-like 1 antibody, LOC423198 antibody, CREB3L1 antibody, Creb3l1 antibody

Background: Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.

Cellular Localization: Endoplasmic reticulum membrane , Processed cyclic AMP-responsive element-binding protein 3-like protein 1: Nucleus

Molecular Weight: 57 kDa

Gene ID: 90993

UniProt: Q96BA8

Pathways: Thyroid Hormone Synthesis, Chromatin Binding