MAML1 antibody (N-Term)

Catalog No. ABIN2855932

Product Details anti-MAML1 Antibody

Target: MAML1 (Mastermind-Like 1 (MAML1))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAML1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Characteristics: Rabbit Polyclonal antibody to MAML1 (mastermind-like protein 1)
MAML1 antibody [N1], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human MAML1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: HeLa , HeLa nucleus , mouse heart

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MAML1

Target: MAML1 (Mastermind-Like 1 (MAML1))

Alternative Name: MAML1 (MAML1 Products)

Synonyms: mam1 antibody, mam-1 antibody, xmam1 antibody, MAML1 antibody, AI644666 antibody, AW743257 antibody, D930008C07Rik antibody, Mam-1 antibody, Mam1 antibody, mKIAA0200 antibody, mastermind like transcriptional coactivator 1 L homeolog antibody, mastermind like transcriptional coactivator 1 antibody, mastermind like 1 (Drosophila) antibody, mastermind-like transcriptional coactivator 1 antibody, maml1.L antibody, MAML1 antibody, Maml1 antibody

Background: This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

Cellular Localization: Nucleus speckle

Molecular Weight: 108 kDa

Gene ID: 9794

Pathways: Notch Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development