SOCS4 antibody (C-Term)

Catalog No. ABIN2855920

Product Details anti-SOCS4 Antibody

Target: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOCS4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to SOCS4 (suppressor of cytokine signaling 4)
SOCS4 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SOCS4. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLaS3

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SOCS4

Target: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Alternative Name: suppressor of cytokine signaling 4 (SOCS4 Products)

Synonyms: SOCS7 antibody, socs4 antibody, SOCS4 antibody, 3110032M18Rik antibody, A730004F22Rik antibody, AI427843 antibody, AU015727 antibody, AU015859 antibody, Socs7 antibody, SOCS6 antibody, socs7 antibody, socs4a antibody, suppressor of cytokine signaling 4 antibody, SOCS4 antibody, socs4 antibody, Socs4 antibody

Background: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 51 kDa

Gene ID: 122809

UniProt: Q8WXH5

Pathways: JAK-STAT Signaling, EGFR Signaling Pathway