ORC4 antibody (C-Term)
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- Target See all ORC4 Antibodies
- ORC4 (Origin Recognition Complex, Subunit 4 (ORC4))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ORC4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Cross-Reactivity
- Human
- Characteristics
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Rabbit Polyclonal antibody to ORC4L (origin recognition complex subunit 4)
ORC4L antibody [C3], C-term - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ORC4L. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product ORC4 Primary Antibody
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: HeLa
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.77 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- ORC4 (Origin Recognition Complex, Subunit 4 (ORC4))
- Alternative Name
- origin recognition complex subunit 4 (ORC4 Products)
- Background
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The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown to form a core complex with ORC2L, -3L, and -5L. Three alternatively spliced transcript variants encoding the same protein have been reported.
Cellular Localization: Nucleus - Molecular Weight
- 50 kDa
- Gene ID
- 5000
- UniProt
- O43929
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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