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MMP7 antibody (C-Term)

MMP7 Reactivity: Human WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855888
  • Target See all MMP7 Antibodies
    MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
    Binding Specificity
    • 16
    • 14
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 70
    • 29
    • 29
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 73
    • 16
    • 1
    Rabbit
    Clonality
    • 76
    • 14
    Polyclonal
    Conjugate
    • 44
    • 10
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MMP7 antibody is un-conjugated
    Application
    • 64
    • 36
    • 30
    • 22
    • 13
    • 13
    • 11
    • 10
    • 9
    • 9
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Cow, Human, Mouse, Rat
    Characteristics
    Rabbit polyclonal antibody to MMP7 (matrix metallopeptidase 7 (matrilysin, uterine))
    MMP7 antibody [C2C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MMP7. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product MMP7 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Validation: Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.45 mg/mL
    Buffer
    1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Cai, Sun, Duan, Qiu, Dai, Yang, He: "FHL2 promotes tubular epithelial-to-mesenchymal transition through modulating β-catenin signalling." in: Journal of cellular and molecular medicine, Vol. 22, Issue 3, pp. 1684-1695, (2019) (PubMed).

    Luo, Liao, Liao, Chen, Huang, Fan, Liao: "The role of kinesin KIF18A in the invasion and metastasis of hepatocellular carcinoma." in: World journal of surgical oncology, Vol. 16, Issue 1, pp. 36, (2018) (PubMed).

    Oelusarz, Nichols, Grunz-Borgmann, Chen, Akintola, Catania, Burghardt, Trzeciakowski, Parrish: "Overexpression of MMP-7 Increases Collagen 1A2 in the Aging Kidney." in: Physiological reports, Vol. 1, Issue 5, (2013) (PubMed).

  • Target
    MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
    Alternative Name
    matrix metallopeptidase 7 (MMP7 Products)
    Synonyms
    MAT antibody, MPMM antibody, MMP-7 antibody, MPSL1 antibody, PUMP-1 antibody, matrilysin antibody, LOC727698 antibody, MMP7 antibody, Matrilysin antibody, matrix metallopeptidase 7 antibody, MMP7 antibody, Mmp7 antibody
    Background
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

    Cellular Localization: Secreted , extracellular space , extracellular matrix
    Molecular Weight
    30 kDa
    Gene ID
    4316
    UniProt
    P09237
    Pathways
    Production of Molecular Mediator of Immune Response
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