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PDE4D antibody (C-Term)

PDE4D Reactivity: Human WB, ICC, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855885
  • Target See all PDE4D Antibodies
    PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))
    Binding Specificity
    • 16
    • 7
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 52
    • 42
    • 42
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 54
    • 1
    • 1
    Rabbit
    Clonality
    • 53
    • 3
    Polyclonal
    Conjugate
    • 28
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDE4D antibody is un-conjugated
    Application
    • 46
    • 21
    • 19
    • 17
    • 11
    • 9
    • 8
    • 6
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human
    Characteristics
    Rabbit Polyclonal antibody to PDE4D (phosphodiesterase 4D, cAMP-specific)
    PDE4D antibody [C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PDE4D. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product PDE4D Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: A431 , HeLa

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.3 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))
    Alternative Name
    phosphodiesterase 4D (PDE4D Products)
    Background
    The PDE4D gene is complex and has at least 9 different isoforms that encode functional proteins. These proteins degrade the second messenger cAMP, which is a key signal transduction molecule in multiple cell types, including vascular cells (Dominiczak and McBride, 2003 [PubMed 14517535]).[supplied by OMIM]

    Cellular Localization: Cytoplasm (By similarity) , Membrane (By similarity) , Cytoplasm , cytoskeleton (By similarity) , Centrosome (By similarity)
    Molecular Weight
    91 kDa
    Gene ID
    5144
    UniProt
    Q08499
    Pathways
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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