FUBP1 antibody

Catalog No. ABIN2855856

Product Details anti-FUBP1 Antibody

Target: FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to FUBP1 (far upstream element-binding protein 1)
FUBP1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human FUBP1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: mouse brain , rat brain

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.92 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-FUBP1 antibody (ABIN2855856)

Kralovicova, Vorechovsky: "Alternative splicing of U2AF1 reveals a shared repression mechanism for duplicated exons." in: Nucleic acids research, Vol. 45, Issue 1, pp. 417-434, (2017) (PubMed).

Kralovicova, Knut, Cross, Vorechovsky: "Exon-centric regulation of ATM expression is population-dependent and amenable to antisense modification by pseudoexon targeting." in: Scientific reports, Vol. 6, pp. 18741, (2016) (PubMed).

Target Details for FUBP1

Target: FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

Alternative Name: far upstream element binding protein 1 (FUBP1 Products)

Synonyms: FBP antibody, FUBP antibody, fbp antibody, fubp antibody, MGC53183 antibody, MGC75632 antibody, FUBP1 antibody, DKFZp468N0812 antibody, 9530027K12Rik antibody, D3Ertd330e antibody, Fubp antibody, Fubp4 antibody, MGC78835 antibody, wu:fa92h11 antibody, wu:fb24h11 antibody, wu:fc26f06 antibody, zgc:66046 antibody, far upstream element binding protein 1 antibody, far upstream element (FUSE) binding protein 1 S homeolog antibody, far upstream element (FUSE) binding protein 1 antibody, far upstream element binding protein 1 L homeolog antibody, FUBP1 antibody, fubp1.S antibody, fubp1 antibody, Fubp1 antibody, fubp1.L antibody

Background: This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase.

Cellular Localization: Nucleus

Molecular Weight: 68 kDa

Gene ID: 8880

UniProt: Q96AE4