CES2 antibody

Catalog No. ABIN2855810

Product Details anti-CES2 Antibody

Target: CES2 (Carboxylesterase 2 (CES2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CES2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to CES2 (carboxylesterase 2)
CES2 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CES2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for CES2

Target: CES2 (Carboxylesterase 2 (CES2))

Alternative Name: carboxylesterase 2 (CES2 Products)

Synonyms: CE-2 antibody, CES2A1 antibody, PCE-2 antibody, iCE antibody, Ces2 antibody, im:6908784 antibody, si:dkey-38l12.2 antibody, zgc:153863 antibody, ce-2 antibody, ces2a1 antibody, pce-2 antibody, carboxylesterase 2 antibody, liver carboxylesterase 2 antibody, cocaine esterase antibody, carboxylesterase 2 (intestine, liver) antibody, CES2 antibody, Ces2 antibody, LOC100343300 antibody, LOC100734360 antibody, ces2 antibody

Background: Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined, however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Cellular Localization: Endoplasmic reticulum lumen

Molecular Weight: 62 kDa

Gene ID: 8824

UniProt: O00748