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PDK3 antibody (Center)

PDK3 Reactivity: Human IHC (p), ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855802
  • Target See all PDK3 Antibodies
    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
    Binding Specificity
    • 9
    • 9
    • 9
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 31
    • 30
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 49
    • 3
    Rabbit
    Clonality
    • 49
    • 3
    Polyclonal
    Conjugate
    • 29
    • 6
    • 5
    • 4
    • 4
    • 4
    This PDK3 antibody is un-conjugated
    Application
    • 46
    • 35
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Cross-Reactivity
    Mouse (Murine), Chicken, Rat (Rattus), Cow (Bovine), Xenopus tropicalis
    Cross-Reactivity (Details)
    Mouse (96 %), Chicken (93 %), Rat (96 %), Bovine (98 %), Xenopus tropicalis (83 %)
    Characteristics
    Rabbit Polyclonal antibody to PDK3 (pyruvate dehydrogenase kinase, isozyme 3)
    PDK3 antibody [N1C2]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human PDK3. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product PDK3 Primary Antibody
  • Application Notes
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000*
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.4 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
    Alternative Name
    PDK3 (PDK3 Products)
    Synonyms
    pdk3 antibody, PDK3 antibody, 2610001M10Rik antibody, AI035637 antibody, zgc:158702 antibody, pyruvate dehydrogenase kinase 3 antibody, pyruvate dehydrogenase kinase, isozyme 3a antibody, pyruvate dehydrogenase kinase, isoenzyme 3 antibody, fragile site, 5-azacytidine type, common, fra(1)(q12) antibody, pyruvate dehydrogenase kinase, isozyme 3b antibody, PDK3 antibody, Pdk3 antibody, pdk3a antibody, pdk3 antibody, FRA1J antibody, pdk3b antibody
    Background
    Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

    Cellular Localization: Mitochondrion matrix
    Molecular Weight
    47 kDa
    Gene ID
    5165
    Pathways
    PI3K-Akt Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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