Kallikrein 11 antibody

Catalog No. ABIN2855789

Product Details anti-Kallikrein 11 Antibody

Target: Kallikrein 11 (KLK11)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to KLK11 (kallikrein-related peptidase 11)
KLK11 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Kallikrein 11. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse brain , Molt-4

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Kallikrein 11

Target: Kallikrein 11 (KLK11)

Alternative Name: kallikrein related peptidase 11 (KLK11 Products)

Synonyms: KLK11 antibody, 2310015I08Rik antibody, Prss20 antibody, TLSP antibody, PRSS20 antibody, kallikrein related peptidase 11 antibody, kallikrein related-peptidase 11 antibody, kallikrein-related peptidase 11 antibody, KLK11 antibody, Klk11 antibody

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in two transcript variants encoding two different isoforms which are differentially expressed.

Cellular Localization: Secreted

Molecular Weight: 31 kDa

Gene ID: 11012

UniProt: Q9UBX7

Pathways: Complement System