TYK2 antibody
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- Target See all TYK2 Antibodies
- TYK2 (Tyrosine Kinase 2 (TYK2))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TYK2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Cross-Reactivity
- Human
- Characteristics
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Rabbit polyclonal antibody to TYK2 (tyrosine kinase 2)
TYK2 antibody [C1C3] - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human TYK2. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product TYK2 Primary Antibody
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anti-Tyrosine Kinase 2 (TYK2) (AA 276-375) antibody
TYK2 Reactivity: Human WB, ELISA, IF, IHC (p), IP Host: Mouse Monoclonal 6G12 unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 276-375) antibodyTYK2 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 6H1 unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 750-850) antibodyTYK2 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) (pTyr1054), (pTyr1055) antibodyTYK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 286-372) antibodyTYK2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) (C-Term) antibodyTYK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) antibodyTYK2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 8G8B3 unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 1-1187) antibodyTYK2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 1020-1069) antibodyTYK2 Reactivity: Human, Mouse WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 915-1173) antibodyTYK2 Reactivity: Human WB, ELISA, IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- TYK2 (Tyrosine Kinase 2 (TYK2))
- Alternative Name
- tyrosine kinase 2 (TYK2 Products)
- Synonyms
- JTK1 antibody, tyrosine kinase 2 antibody, TYK2 antibody, Tyk2 antibody
- Background
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This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
- Molecular Weight
- 134 kDa
- Gene ID
- 7297
- UniProt
- P29597
- Pathways
- JAK-STAT Signaling, Hepatitis C
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