Protocadherin 1 antibody

Catalog No. ABIN2855706

Product Details anti-Protocadherin 1 Antibody

Target: Protocadherin 1 (PCDH1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Protocadherin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to Protocadherin-1 (protocadherin 1)
PCDH1 antibody [N1N3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PCDH1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.87 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Protocadherin 1

Target: Protocadherin 1 (PCDH1)

Alternative Name: protocadherin 1 (PCDH1 Products)

Synonyms: PC42 antibody, PCDH42 antibody, 2010005A06Rik antibody, AI585920 antibody, PCDH-1 antibody, axpc antibody, protocadherin-1 antibody, pcdh1 antibody, protocadherin 1 antibody, protocadherin 1 S homeolog antibody, protocadherin 1b antibody, PCDH1 antibody, Pcdh1 antibody, pcdh1.S antibody, pcdh1b antibody

Background: This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.

Cellular Localization: Cell junction , Cell membrane, Single-pass type I membrane protein (Probable)

Molecular Weight: 115 kDa

Gene ID: 5097

UniProt: Q08174