Laminin beta 3 antibody

Catalog No. ABIN2855691

Product Details anti-Laminin beta 3 Antibody

Target: Laminin beta 3 (LAMB3) (Laminin, beta 3 (LAMB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Laminin beta 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to Laminin beta 3 (laminin, beta 3)
Laminin beta 3 antibody [C1C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Laminin beta 3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: NIH-3T3 , A431

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.46 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Laminin beta 3

Target: Laminin beta 3 (LAMB3) (Laminin, beta 3 (LAMB3))

Alternative Name: laminin subunit beta 3 (LAMB3 Products)

Synonyms: LAMB3 antibody, lam5 antibody, lamnb1 antibody, BM600-125KDA antibody, LAM5 antibody, LAMNB1 antibody, laminin subunit beta 3 antibody, laminin, beta 3 antibody, LAMB3 antibody, lamb3 antibody, Lamb3 antibody

Background: The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene.

Cellular Localization: Secreted , extracellular space , extracellular matrix , basement membrane

Molecular Weight: 130 kDa

Gene ID: 3914

UniProt: Q13751

Pathways: Brown Fat Cell Differentiation