LRRN2 antibody

Catalog No. ABIN2855658

Product Details anti-LRRN2 Antibody

Target: LRRN2 (Leucine Rich Repeat Neuronal 2 (LRRN2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to LRRN2 (leucine rich repeat neuronal 2)
LRRN2 antibody [N2C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human LRRN2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: U87-MG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for LRRN2

Target: LRRN2 (Leucine Rich Repeat Neuronal 2 (LRRN2))

Alternative Name: leucine rich repeat neuronal 2 (LRRN2 Products)

Synonyms: GAC1 antibody, LRRN5 antibody, LRANK1 antibody, FIGLER7 antibody, LRRN2 antibody, leucine rich repeat neuronal 2 antibody, LRRN2 antibody, Lrrn2 antibody

Background: The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Cellular Localization: Membrane, Single-pass type I membrane protein

Molecular Weight: 79 kDa

Gene ID: 10446

UniProt: O75325