Desmin antibody
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- Target See all Desmin (DES) Antibodies
- Desmin (DES)
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Desmin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- Cross-Reactivity
- Cat, Chicken, Dog, Human, Mouse, Pig, Rat
- Characteristics
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Rabbit Polyclonal antibody to Desmin (desmin)
Desmin antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human Desmin. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product DES Primary Antibody
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- Application Notes
- WB: 1:500-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: A549 , HCT116 , 50 μg mouse muscle , Rat2
Validation: Orthogonal
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.62 mg/mL
- Buffer
- 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7), 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- Desmin (DES)
- Alternative Name
- desmin (DES Products)
- Background
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This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
Cellular Localization: Cytoplasm - Molecular Weight
- 54 kDa
- Gene ID
- 1674
- UniProt
- P17661
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