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Kallikrein 7 antibody

KLK7 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855653
  • Target See all Kallikrein 7 (KLK7) Antibodies
    Kallikrein 7 (KLK7)
    Reactivity
    • 43
    • 30
    • 18
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 71
    • 6
    Rabbit
    Clonality
    • 74
    • 3
    Polyclonal
    Conjugate
    • 28
    • 13
    • 11
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Kallikrein 7 antibody is un-conjugated
    Application
    • 48
    • 30
    • 25
    • 13
    • 13
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Rabbit Polyclonal antibody to KLK7 (kallikrein-related peptidase 7)
    KLK7 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Kallikrein 7. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product KLK7 Primary Antibody
  • Application Notes
    WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Kallikrein 7-transfected 293T

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.69 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Delaunay, Deschamps, Haddada, Walker, Soosaipillai, Soualmia, El Amri, Diamandis, Brattsand, Magdolen, Darmoul: "Aberrant expression of kallikrein-related peptidase 7 is correlated with human melanoma aggressiveness by stimulating cell migration and invasion." in: Molecular oncology, Vol. 11, Issue 10, pp. 1330-1347, (2018) (PubMed).

  • Target
    Kallikrein 7 (KLK7)
    Alternative Name
    kallikrein related peptidase 7 (KLK7 Products)
    Synonyms
    Prss6 antibody, SCCE antibody, PRSS6 antibody, hK7 antibody, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) antibody, kallikrein-related peptidase 7 antibody, kallikrein related peptidase 7 antibody, Klk7 antibody, KLK7 antibody
    Background
    Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein.

    Cellular Localization: Secreted
    Molecular Weight
    28 kDa
    Gene ID
    5650
    UniProt
    P49862
    Pathways
    Complement System
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