FPGS antibody

Catalog No. ABIN2855645

Product Details anti-FPGS Antibody

Target: FPGS (Folylpolyglutamate Synthase (FPGS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPGS antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to Folylpolyglutamate synthase (folylpolyglutamate synthase)
Folylpolyglutamate synthase antibody [N3C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Folylpolyglutamate synthase. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: FPGS transfected 293T

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FPGS

Target: FPGS (Folylpolyglutamate Synthase (FPGS))

Alternative Name: folylpolyglutamate synthase (FPGS Products)

Synonyms: zgc:63807 antibody, wu:fk49h03 antibody, wu:fk51d09 antibody, FPGS antibody, fpgS antibody, SCC88.25c antibody, BA4689 antibody, AA408187 antibody, folylpolyglutamate synthase antibody, dihydrofolate synthase antibody, folylpolyglutamate synthase, mitochondrial antibody, folylpolyglutamyl synthetase antibody, fpgs antibody, fpgS antibody, FPGS antibody, SCO2614 antibody, fgs antibody, folC antibody, CpipJ_CPIJ008043 antibody, Fpgs antibody

Background: This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms.

Cellular Localization: Mitochondrion , Cytoplasm

Molecular Weight: 65 kDa

Gene ID: 2356

UniProt: Q05932