ORC2 antibody

Catalog No. ABIN2855601

Product Details anti-ORC2 Antibody

Target: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to ORC2 (origin recognition complex, subunit 2-like (yeast))
ORC2 antibody [N3C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ORC2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ORC2

Target: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Alternative Name: origin recognition complex subunit 2 (ORC2 Products)

Synonyms: CG3041 antibody, DmORC 2 antibody, DmORC2 antibody, DmOrc2 antibody, DmOrc2p antibody, Dmel\\CG3041 antibody, ORC antibody, ORC2 antibody, Orc-2 antibody, Orc2p antibody, fs(3)293 antibody, fs(3)293-19 antibody, k43 antibody, l(3)88Ab antibody, l(3)A5 antibody, l(3)K43 antibody, l(3)SG44 antibody, l(3)dsl5 antibody, l(3)k43 antibody, orc2 antibody, rDmORC antibody, ATORC2 antibody, F13M22.6 antibody, F13M22_6 antibody, ORIGIN RECOGNITION COMPLEX SECOND LARGEST SUBUNIT 2 antibody, origin recognition complex second largest subunit 2 antibody, ORC2L antibody, AU041563 antibody, Orc2l antibody, orc2-a antibody, orc2l antibody, xorc2 antibody, Origin recognition complex subunit 2 antibody, origin recognition complex second largest subunit 2 antibody, origin recognition complex subunit 2 antibody, origin recognition complex, subunit 2 antibody, origin recognition complex subunit 2 S homeolog antibody, Orc2 antibody, ORC2 antibody, orc2.S antibody, orc-2 antibody

Background: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3L, -4L, and -5L. It also interacts with CDC45L and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication.

Cellular Localization: Nucleus

Molecular Weight: 66 kDa

Gene ID: 4999

UniProt: Q13416