ARHGDIB antibody

Catalog No. ABIN2855594

Product Details anti-ARHGDIB Antibody

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGDIB antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit polyclonal antibody to Rho GDI2 (Rho GDP dissociation inhibitor (GDI) beta)
Rho GDI2 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Rho GDI2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ARHGDIB

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Alternative Name: Rho GDP dissociation inhibitor beta (ARHGDIB Products)

Synonyms: ARHGDIB antibody, zgc:65966 antibody, arhgdib antibody, MGC69067 antibody, gdia2 antibody, rhodgi-2 antibody, rhodgi2 antibody, D4 antibody, GDIA2 antibody, GDID4 antibody, LYGDI antibody, Ly-GDI antibody, RAP1GN1 antibody, RhoGDI2 antibody, Gdid4 antibody, Rho GDP dissociation inhibitor (GDI) gamma antibody, Rho GDP dissociation inhibitor (GDI) beta S homeolog antibody, Rho GDP dissociation inhibitor beta antibody, Rho GDP dissociation inhibitor (GDI) beta antibody, Rho, GDP dissociation inhibitor (GDI) beta antibody, arhgdig antibody, arhgdib.S antibody, ARHGDIB antibody, arhgdib antibody, Arhgdib antibody

Background: Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM]

Cellular Localization: Cytoplasm

Molecular Weight: 23 kDa

Gene ID: 397

UniProt: P52566

Pathways: Caspase Cascade in Apoptosis