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TFAM antibody

KO Validated TFAM Reactivity: Human WB, IF, IP, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855585
  • Target See all TFAM Antibodies
    TFAM (Transcription Factor A, Mitochondrial (TFAM))
    Reactivity
    • 52
    • 29
    • 25
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 79
    • 4
    Rabbit
    Clonality
    • 71
    • 12
    Polyclonal
    Conjugate
    • 39
    • 8
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TFAM antibody is un-conjugated
    Application
    • 63
    • 30
    • 21
    • 20
    • 17
    • 14
    • 14
    • 14
    • 11
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Rabbit Polyclonal antibody to mtTFA (transcription factor A, mitochondrial)
    mtTFA antibody
    Purification
    Purified by antigen-affinity chromatography.
    Grade
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human mtTFA. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product TFAM Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: 293T , A431 , HeLa , HepG2

    Validation: KO/KD, Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.23 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    TFAM (Transcription Factor A, Mitochondrial (TFAM))
    Alternative Name
    transcription factor A, mitochondrial (TFAM Products)
    Background
    This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.

    Cellular Localization: Mitochondrion
    Molecular Weight
    29 kDa
    Gene ID
    7019
    UniProt
    Q00059
    Pathways
    Chromatin Binding
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