Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

NRF1 antibody

NRF1 Reactivity: Human WB, IHC (p), IF, ICC, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855569
  • Target See all NRF1 Antibodies
    NRF1 (Nuclear Respiratory Factor 1 (NRF1))
    Reactivity
    • 71
    • 43
    • 36
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 68
    • 5
    Rabbit
    Clonality
    • 60
    • 13
    Polyclonal
    Conjugate
    • 36
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NRF1 antibody is un-conjugated
    Application
    • 60
    • 29
    • 14
    • 14
    • 13
    • 11
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Rabbit Polyclonal antibody to NRF1 (nuclear respiratory factor 1)
    NRF1 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human NRF1. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product NRF1 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: 293T nuclear , A431 nuclear , HeLa nuclear , HepG2 nuclear

    Validation: Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.32 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Mesquita, Lamb, Parry, Moore, Smith, Vann, Osburn, Fox, Ruple, Huggins, Fruge, Young, Kavazis, Roberts: "Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults." in: Physiological reports, Vol. 8, Issue 15, pp. e14526, (2020) (PubMed).

    Ma, Cheng, Mu, Geng, Zhao, Luo, Ma, Chang, Liu, Gao, Nie, Xie, Han, Chen, Ma, Zhu, Chen: "The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression." in: Nature communications, Vol. 10, Issue 1, pp. 1034, (2019) (PubMed).

  • Target
    NRF1 (Nuclear Respiratory Factor 1 (NRF1))
    Alternative Name
    nuclear respiratory factor 1 (NRF1 Products)
    Synonyms
    ALPHA-PAL antibody, C87038 antibody, D6Ertd415e antibody, SC:BZ3C13.1 antibody, SC:bZ3C13.2 antibody, ube2h antibody, Nfe2l1_retired antibody, IBR/F antibody, NRF1 antibody, alpha-pal antibody, nrf-1 antibody, LOC100220087 antibody, nuclear respiratory factor 1 antibody, nuclear respiratory factor 1 S homeolog antibody, NRF1 antibody, Nrf1 antibody, nrf1 antibody, nrf1.S antibody
    Background
    This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1.

    Cellular Localization: Nucleus
    Molecular Weight
    54 kDa
    Gene ID
    4899
    UniProt
    Q16656
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
You are here:
Support