SP1 antibody (C-Term)
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- Target See all SP1 Antibodies
- SP1 (Sp1 Transcription Factor (SP1))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SP1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Cross-Reactivity
- Human
- Characteristics
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Rabbit Polyclonal antibody to SP1 (Sp1 transcription factor)
SP1 antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the C-terminus region of human SP1. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product SP1 Primary Antibody
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anti-Sp1 Transcription Factor (SP1) (pThr453) antibody
SP1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 677-707), (C-Term) antibodySP1 Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB17350 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibodySP1 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 1A5 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 522-618) antibodySP1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4B11 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibodySP1 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 4H6 unconjugated
anti-Sp1 Transcription Factor (SP1) antibodySP1 Reactivity: Human WB, IHC, IF, ChIP Host: Rabbit Monoclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (pThr739) antibodySP1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-199) antibodySP1 Reactivity: Human, Mouse WB, ELISA, IF Host: Mouse Monoclonal 4H6 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 420-620) antibodySP1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 677-707) antibodySP1 Reactivity: Human WB, ELISA, IHC, IF, FACS Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: THP-1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- SP1 (Sp1 Transcription Factor (SP1))
- Alternative Name
- Sp1 transcription factor (SP1 Products)
- Background
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Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
Cellular Localization: Nucleus - Molecular Weight
- 81 kDa
- Gene ID
- 6667
- UniProt
- P08047
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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