Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

DIAPH3 antibody (Center)

DIAPH3 Reactivity: Human IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855508
  • Target See all DIAPH3 Antibodies
    DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))
    Binding Specificity
    • 15
    • 9
    • 9
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 43
    • 17
    • 9
    Human
    Host
    • 53
    • 4
    • 1
    Rabbit
    Clonality
    • 56
    • 2
    Polyclonal
    Conjugate
    • 23
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DIAPH3 antibody is un-conjugated
    Application
    • 45
    • 24
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Cow (Bovine)
    Cross-Reactivity (Details)
    Bovine (90 %)
    Characteristics
    Rabbit polyclonal antibody to DIAPH3 (diaphanous homolog 3 (Drosophila))
    DIAPH3 antibody [C1C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human DIAPH3. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product DIAPH3 Primary Antibody
  • Application Notes
    Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000*
    Comment

    Positive Control: Target recombinant protein

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))
    Alternative Name
    DIAPH3 (DIAPH3 Products)
    Synonyms
    Diap3 antibody, DIAP3 antibody, DIAPH3 antibody, 4930417P13Rik antibody, Dia2 antibody, Diaph3 antibody, Drf3 antibody, mDia2 antibody, mKIAA4117 antibody, p134MDia2 antibody, AN antibody, AUNA1 antibody, DIA2 antibody, DRF3 antibody, NSDAN antibody, diap3 antibody, diaphanous-related formin 3 antibody, diaphanous related formin 3 antibody, diaphanous homolog 3 (Drosophila) antibody, Diaph3 antibody, DIAPH3 antibody
    Background
    Binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics.

    Molecular Weight
    137 kDa
    Gene ID
    81624
You are here:
Support