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PRPS1 antibody (N-Term)

PRPS1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855446
  • Target See all PRPS1 Antibodies
    PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))
    Binding Specificity
    • 3
    • 1
    • 1
    N-Term
    Reactivity
    • 8
    • 3
    • 2
    Human
    Host
    • 5
    • 3
    Rabbit
    Clonality
    • 6
    • 2
    Polyclonal
    Conjugate
    • 8
    This PRPS1 antibody is un-conjugated
    Application
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Rabbit Polyclonal antibody to PRPS1 (phosphoribosyl pyrophosphate synthetase 1)
    PRPS1 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the N-terminus region of human PRPS1. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Mouse kidney , Rat liver , 293T

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.58 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))
    Alternative Name
    phosphoribosyl pyrophosphate synthetase 1 (PRPS1 Products)
    Synonyms
    ARTS antibody, CMTX5 antibody, DFN2 antibody, DFNX1 antibody, PPRibP antibody, PRS-I antibody, PRSI antibody, 2310010D17Rik antibody, C76571 antibody, C76678 antibody, Prps-1 antibody, cb96 antibody, prps1 antibody, wu:fa18f03 antibody, wu:fb33h12 antibody, wu:fd26g08 antibody, zgc:55299 antibody, zgc:76932 antibody, arts antibody, cmtx5 antibody, ppribp antibody, prsi antibody, fc64g03 antibody, im:6909503 antibody, wu:fc64g03 antibody, zgc:153331 antibody, phosphoribosyl pyrophosphate synthetase 1 antibody, phosphoribosyl pyrophosphate synthetase 1A antibody, phosphoribosyl pyrophosphate synthetase 1 L homeolog antibody, phosphoribosyl pyrophosphate synthetase 1B antibody, PRPS1 antibody, Prps1 antibody, prps1a antibody, prps1.L antibody, prps1b antibody
    Background
    This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome.

    Molecular Weight
    35 kDa
    Gene ID
    5631
    UniProt
    P60891
    Pathways
    Ribonucleoside Biosynthetic Process
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