CDC42BPA antibody

Catalog No. ABIN2855436

Product Details anti-CDC42BPA Antibody

Target: CDC42BPA (CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC42BPA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to MRCK alpha (CDC42 binding protein kinase alpha (DMPK-like))
MRCK alpha antibody

Purification: Affinity purified by Protein A.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MRCK alpha. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: U87-MG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for CDC42BPA

Target: CDC42BPA (CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA))

Alternative Name: CDC42 binding protein kinase alpha (CDC42BPA Products)

Synonyms: MRCK antibody, MRCKA antibody, PK428 antibody, Mrck antibody, Pk428 antibody, A930014J19Rik antibody, DMPK-like antibody, CDC42BPA antibody, CDC42 binding protein kinase alpha antibody, GDNF family receptor alpha 2 antibody, serine/threonine-protein kinase MRCK alpha antibody, CDC42 binding protein kinase alpha (DMPK-like) antibody, CDC42BPA antibody, Cdc42bpa antibody, GFRA2 antibody, LOC100182779 antibody, LOC100545977 antibody

Background: The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.

Cellular Localization: Cytoplasm (By similarity)

Molecular Weight: 197 kDa

Gene ID: 8476

UniProt: Q5VT25