FASTK antibody (C-Term)
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- Target See all FASTK Antibodies
- FASTK (Fas-Activated serine/threonine Kinase (FASTK))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FASTK antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
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Rabbit Polyclonal antibody to FAST (Fas-activated serine/threonine kinase)
FAST antibody - Purification
- Affinity purified by Protein A.
- Immunogen
- Recombinant protein encompassing a sequence within the C-terminus region of human FAST. The exact sequence is proprietary.
- Isotype
- IgG
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: 293T , A431 , HeLa , HepG2 , A375 , NIH-3T3 , PC-12
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 6.56 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- FASTK (Fas-Activated serine/threonine Kinase (FASTK))
- Alternative Name
- Fas activated serine/threonine kinase (FASTK Products)
- Synonyms
- FASTK antibody, DKFZp469E0832 antibody, FAST antibody, 0610011K02Rik antibody, 610011K02Rik antibody, Fas activated serine/threonine kinase antibody, Fas-activated serine/threonine kinase antibody, FASTK antibody, Fastk antibody
- Background
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The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.
- Molecular Weight
- 61 kDa
- Gene ID
- 10922
- UniProt
- Q14296
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