NTRK3 antibody (Internal Region)
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- Target See all NTRK3 Antibodies
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NTRK3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Rhesus Monkey
- Cross-Reactivity (Details)
- Rhesus Monkey (100 %)
- Characteristics
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Rabbit polyclonal antibody to TrkC (neurotrophic tyrosine kinase, receptor, type 3)
TrkC antibody [N2C1], Internal - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human TrkC. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product NTRK3 Primary Antibody
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- Application Notes
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
- Comment
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Positive Control: 293T , A431 , H1299 , HeLaS3 , Molt-4 , Raji , NIH-3T3
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
- Alternative Name
- TrkC (NTRK3 Products)
- Synonyms
- TRKC antibody, gp145(trkC) antibody, trkC antibody, AW125844 antibody, Ntrk3_tv3 antibody, TrkC antibody, neurotrophic receptor tyrosine kinase 3 antibody, neurotrophic tyrosine kinase, receptor, type 3 antibody, NTRK3 antibody, Ntrk3 antibody
- Background
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This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Cellular Localization: Membrane, Single-pass type I membrane protein - Molecular Weight
- 94 kDa
- Gene ID
- 4916
- Pathways
- RTK Signaling, Neurotrophin Signaling Pathway, Regulation of Cell Size
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