NME5 antibody (Center)

Catalog No. ABIN2855404

Product Details anti-NME5 Antibody

Target: NME5 (NME/NM23 Family Member 5 (NME5))

Binding Specificity: Center

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NME5 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Cow (Bovine)

Cross-Reactivity (Details): Bovine (88 %)

Characteristics: Rabbit polyclonal antibody to NME5 (non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase))
NME5 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human NME5. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: A431 , HeLa , NIH-3T3

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.22 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for NME5

Target: NME5 (NME/NM23 Family Member 5 (NME5))

Alternative Name: NME5 (NME5 Products)

Synonyms: NM23-H5 antibody, NM23H5 antibody, RSPH23 antibody, 1700019D05Rik antibody, Nm23-M5 antibody, NME/NM23 family member 5 antibody, non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase) antibody, NME5 antibody, Nme5 antibody

Background: Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species.

Molecular Weight: 24 kDa

Gene ID: 8382

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling