Albumin antibody (C-Term)

Catalog No. ABIN2855392

Product Details anti-Albumin Antibody

Key Features:

• High quality Albumin Primary Antibody for the detection of ALB.
• Reliable product with high standard validation data

Target: Albumin (ALB)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Albumin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Cat, Dog, Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to Albumin antibody
Albumin antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Albumin. The exact sequence is proprietary.

Isotype: IgG

Product Specific Information:

What can the Albumin Antibody ABIN2855392 be used for?: This polyclonal Albumin Antibody detects Albumin. The Albumin Antibody has been validated for various applications and can be used for the detection of Albumin and derivatives by Western Blotting, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin-embedded Sections), Immunohistochemistry (Frozen Sections).

What validation data is available for this Albumin Antibody?: The primary antibody is referenced in 4 publications and is characterized by a proven, very high reliability. It has currently 5 product images that show its performance in a variety of applications. The product is currently available in 100 μL quantity. Albumin Antibody for the detection of Albumin and derivatives.

What is the function of Albumin?: Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008].

Application Details

Application Notes: WB: 1:500-1:100000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.45 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-Albumin antibody (ABIN2855392)

Gan, Patterson, Watanabe, Wang, Edmonds, Reinholdt, Sucov: "Allelic variants between mouse substrains BALB/cJ and BALB/cByJ influence mononuclear cardiomyocyte composition and cardiomyocyte nuclear ploidy." in: Scientific reports, Vol. 10, Issue 1, pp. 7605, (2020) (PubMed).

Chung, Huang, Chu, Chen, Lin, Huang, Wu, Huang, Hu, Kao, Tai: "BMP-2 restoration aids in recovery from liver fibrosis by attenuating TGF-β1 signaling." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 98, Issue 8, pp. 999-1013, (2019) (PubMed).

Willis, Pratt, Morris: "Distortion of protein analysis in primary neuronal cultures by serum albumin from culture medium: A methodological approach to improve target protein quantification." in: Journal of neuroscience methods, Vol. 308, pp. 1-5, (2019) (PubMed).

Shih, Ho, Chen, Tsao: "Pigment epithelium-derived factor (PEDF) peptide promotes the expansion of hepatic stem/progenitor cells via ERK and STAT3-dependent signaling." in: American journal of translational research, Vol. 9, Issue 3, pp. 1114-1126, (2017) (PubMed).

Target Details for Albumin

Target: Albumin (ALB)

Alternative Name: albumin (ALB Products)

Synonyms: PRO0883 antibody, PRO0903 antibody, PRO1341 antibody, ALB antibody, CSA antibody, Alb-1 antibody, Alb1 antibody, Albza antibody, LOC100136344 antibody, alb-a antibody, alb-b antibody, albumin antibody, serum albumin 1 antibody, albumin S homeolog antibody, ALB antibody, Alb antibody, LOC100136344 antibody, alb.S antibody

Background: Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin.

Cellular Localization: Secreted

Molecular Weight: 69 kDa

Gene ID: 213

UniProt: P02768

Pathways: Lipid Metabolism