EEF1A2 antibody
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- Target See all EEF1A2 Antibodies
- EEF1A2 (Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EEF1A2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- Based on a BLAST result, it may also cross with human EEF1A1.
- Cross-Reactivity
- Human, Mouse, Rat, Zebrafish (Danio rerio)
- Characteristics
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Rabbit Polyclonal antibody to EEF1A2 (eukaryotic translation elongation factor 1 alpha 2)
EEF1A2 antibody - Purification
- Purified by antigen-affinity chromatography.
- Grade
- KO Validated
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human EEF1A2. The exact sequence is proprietary.
- Isotype
- IgG
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- Application Notes
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: Mouse brain , mouse muscle , rat brain , 293T
Validation: KO/KD
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.21 mg/mL
- Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin." in: Scientific reports, Vol. 6, pp. 35100, (2018) (PubMed).
: "
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Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin." in: Scientific reports, Vol. 6, pp. 35100, (2018) (PubMed).
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- Target
- EEF1A2 (Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2))
- Alternative Name
- eukaryotic translation elongation factor 1 alpha 2 (EEF1A2 Products)
- Synonyms
- EEF1AL antibody, EF-1-alpha-2 antibody, EF1A antibody, HS1 antibody, STN antibody, STNL antibody, EEF1A2 antibody, Eef1a antibody, S1 antibody, wasted antibody, wst antibody, Ps10 antibody, RATPS10 antibody, Stnl antibody, eef1al antibody, ef1a antibody, stnl antibody, EEF1A-2 antibody, zgc:92085 antibody, eukaryotic translation elongation factor 1 alpha 2 antibody, eukaryotic translation elongation factor 1 alpha 1 antibody, eukaryotic translation elongation factor 1 alpha 2 S homeolog antibody, putative elongation factor 1-alpha-like 3 antibody, EEF1A2 antibody, EEF1A1 antibody, Eef1a2 antibody, eef1a2.S antibody, eef1a2 antibody, LOC739210 antibody, EEF1 antibody, eef1 antibody
- Background
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This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Nucleus - Molecular Weight
- 50 kDa
- Gene ID
- 1917
- UniProt
- Q05639
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